Statistical data
All calculations were performed with SPSS V.14.0 (SPSS Inc.)parisons between groups were performed using the Student’s t-test, ? 2 test and Fisher’s exact test, and the data were expressed as mean±SD for continuous variables. A p value of <0.05 was considered statistically significant.
Performance
The latest subjects in the current investigation have been 793 clients that have MP pneumonia and you may 384 patients having RWE in the studies period. Having epidemiological testing, an entire 793 patients were utilized, since found for the in the past published blog post.14 Getting systematic evaluation involving the groups, a total of 501 MP pneumonia people that have been acknowledge while in the new previous epidemics (241 times during the 2007–2006, and 260 times in 2011), and you can 384 people that have RWE was analysed (shape step one). Into the studies months, the number of admitted clients during the all of our service is good complete twenty-five 911 (except garden center clients). There had been whenever 2100 admitted people a-year with a few variations inside yearly.
A lot of MP pneumonia patients had pursue-right up period about three years of history crisis year off 2011, although pursue-up victims satisfied with the choice criteria was basically 180 certainly one of 501 circumstances 
regarding MP pneumonia category and you may 206 certainly 384 instances throughout the RWE classification.
For the MP pneumonia clients, there were obvious outbreaks of times during the 2003, 2006–2007 and you will 2011, with cases happening regarding the interepidemic episodes. There have been seemingly constant numbers of RWE instances on a yearly basis through the the study several months. There are zero corresponding improved cases into the MP pneumonia epidemic age except in 2007 (shape dos). Zero MP pneumonia patient who was readmitted because of MP reinfection over the epidemics are seen during the research several months. The fresh new indicate ages and you can years distribution was basically equivalent, and also the height age range were 2–5 years old in both communities (figure step 3). Into the seasonality off one another organizations, MP pneumonia was prevalent in decreasing acquisition off fall, june, winter and you will spring, when you’re patients with RWE have been extremely common inside fall, with spring season, winter and you will summer (study not shown).
Group and you may scientific functions regarding MP pneumonia and RWE organizations
Demographic, clinical and laboratory data in both groups are shown in table 1. The mean age and age distribution were similar in both groups as shown in figure 3 (5.4 years vs 5.6 years, p=0.312). Both groups had male predominance, and there were more males in the RWE group. As expected, cases with wheezing at presentation, the proportion of patients with history or family history of allergic diseases, and history of wheezing were higher in the RWE group. Recurrent wheezing after discharge was observed in 38 of 180 patients with MP pneumonia and 141 of the 206 patients with RWE (p<0.001).
In MP pneumonia patients, 52 of the total 501 patients (10.4%) had wheezing at presentation, 72 (14.4%) had a history of allergic diseases, 15 (3%) had RWE according to our definition and 40 (8%) had a family history of allergic diseases. When we divided the MP pneumonia patients into two groups of patients with wheezing (n=52) and without wheezing (n=449), the patients with wheezing were younger (3.7 years vs 5.6 years, p<0.001) and had higher proportions of history allergic diseases and wheezing history and higher values of leucocyte count and eosinophil differential (table 2). Among the 52 MP pneumonia patients with wheezing at admission, 10 were patient with RWE, while 42 had no previous RWE history. Thus, in this study, 66% (10 of 15) of patients with RWE history presented with wheezing, while 8.6% of patients without RWE history (42 of 486) had wheezing at presentation. In a follow-up study of patients who visited two or more times after discharge, 13 (including 5 cases of RWE) of 21 MP pneumonia patients with initial wheezing and 25 (including 2 cases of RWE) of 159 MP pneumonia patients without wheezing had at least one wheezing episode after discharge (table 2). Although not all patients were followed-up, it was estimated that at least 31 of the total MP pneumonia patients (n=501, 6.2%) showed a recurrent wheezing after initial MP infection.